Sedating muscle relaxant

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While cyclobenzaprine may not share the dangerous cardiac and neurological potential of its close relatives the TCAs, it does share other properties, particularly confusion, lethargy, and anticholinergic side effects, and may have some toxicity in overdose and in combination with other substances.Carisoprodol presents the most significant concern, due particularly to its potential for dependence and abuse.This review investigates the efficacy, side effects, and safety of three commonly prescribed skeletal muscle relaxants metaxalone (Skelaxin), cyclobenzaprine (Flexeril), and carisoprodol (Soma).Muscle relaxants are not really a class of drugs, but rather a group of different medications that produce an overall sedative effect on the body.

Some believe that most of the benefit seen with carisoprodol is secondary to a generalized sedative effect.

Its mode of action may be due to general central nervous system depression.

All three drugs appear to have equal efficacy, but their side effects vary considerably.

Carisoprodol: The action of carisoprodol is related to a central nervous system (CNS) mechanism and not to a direct effect on skeletal muscles.

Carisoprodol acts on the spinal cord and subcortical levels of the brain to depress polysynaptic neuron transmission.

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